Calotropis gigantea crown flower is a species of calotropis native to. Calotropis gigantea arka uses, dose, side effects, ayurveda. Extraction of plant latex is a complex emulsion of polymer micro particles in an aqueous medium. Antimicrobial activity of akanda calotropis gigantea l.
The agar diffusion test was used to check the antimicrobial activity of the. Review of literature ayurvedic system of medicine is widely practised and accepted by an estimated 65% of the population in rural areas in india. Studies on antidiarrheal activity of calotropis gigantea r. Br leaves eecg was investigated in pylorus ligation and ethanol induced ulcer models in experimental rats.
Calotropis gigantea is one such plant found widespread in most of the agricultural and nonagricultural fields. University rewa india nbri lucknow india abstract herbals plants are effective source of traditional and. Can you please tell me the place from where i can get them in large quantity so that my work can be easily started. The green fruits contain a toxic milky sap that is extremely bitter and turns into a gluey coating which is resistant to soap. The plant is erect, tall, large, much branched and perennial with milky latex throughout.
Shahzaib, abdullah khan, arif waqar zaif, wasim ahmed department of biotechnology, university of science and technology bannu, khyber pakhtunkhwa pakistan key words. Evaluation of antibacterial activity of calotropis gigentica against. It has one of the important traditional medicines to treat. Pdf antidiabetic activity of calotropis gigantea in. Ethanolic extract of calotropis gigantea at a dose of 150 and 300mgkg produced significant inhibition of the gastric lesions induced by pylorus. Wound healing activity of latex of c alotropis gigantea article pdf available in international journal of pharmacy and pharmaceutical sciences 11. Chitme hr, chandra r, kaushik s, evaluation of antipyretic activity of calotropis gigantea asclepiadaceae in experimental animals. All structured data from the file and property namespaces is available under the creative commons cc0 license.
Preliminary phytochemical screening of calotropis gigantea leaf. Understanding how this highly adapted plant persists in harsh environments should inform future efforts to improve the hardiness of crop and forage plant species. Significant activity was shown by calotropis gigantea doses as compared to control. Introduction inflammation is defined as the local response of living mammalian to injury due to agent. Calotropis gigantea latex, antifungal activity, minimum fungicidal concentration, zone of inhibition, disc diffusion method correspondence to author. Evaluation of antibacterial activity of calotropis gigentica. The antimicrobial activity of crude aqueous extract of latex of calotropis gigantea apocynaceae was tested against six pathogenic species of bacteria staphylococcus aureus, bacillus cereus, escherichia coli, micrococcus luteus, klebsiella pneumoniae and pseudomonas aeruginosa and two species of fungi candida krusei and aspergillus niger. Fresh calotropis gigentica leaves were collected from the wasteland of jaipur and after washing shade dried at room temperature for 34 days. Pdf the antibacterial activity of methanol extract from the root bark of akanda calotropis gigantea l.
Batch extraction the objective of the batch experiments is to measure the global kinetics of extraction and to investigate the influences of the operating parameters. Evaluation of antibacterial activity of calotropis gigantea latex extr. Asclepiadaceae was tested orally in albino rats at the dose level of 250 and 500 mgkg bodyweight for cns activity. It is a very common herb seen widely throughout india. The study was approved by the institutional animal ethical committee of b. The present study was carried out to evaluate the antioxidant and antibacterial activity of leaves extracts of calotropis procera and calotropis gigantea. Leaves and flowers in streptozotocininduced diabetic rats. Pdf the antimicrobial activity of crude aqueous extract of latex of calotropis gigantea apocynaceae was tested against six pathogenic species of. Dec 03, 2010 to evaluate the hypoglycemic and antidiabetic activity of chloroform extract of calotropis gigantea leaves and flowers in normal rats and streptozotocin induced diabetes. International journal of scientific and research publications, volume 4, issue 2, february 2014 1 issn 22503153.
The leaves are broadly elliptical to oblongobovate in shape, with the size of 920 cm x 612. Pdf many drugs commonly used today are of herbal origin. Name of species calotropis gigantea common name milkweed, swet ark family apocynaceae photo taken on 12 july, 2008 at sadashiv jyotirling, kukas, jaipur, rajasthan description dry leaf powder used for treating wounds and boils. Result of the antimicrobial activity of root extracts of calotropis gigantea. Chemical composition of calotropis gigantea springerlink. Preliminary phytochemical screening and gc ms issn. Mudarol, the chief resinol component of the root bark ofcalotropis gigantea, has been separated into two isomeric compounds by fractional crystallisation of the acetates and also by chromatographic adsorption analysis of the free alcohols. In ovalbumin induced asthma, rats were sensitized and challenged with ovalbumin ova. Antibacterial and phytochemical studies on calotropis gigantia l. The plant has oval, light green leaves and milky stem. Venkatesan saratha and sorimuthu pillai subramanian department of biochemistry, university of madras guindy campus, chennai, tamil nadu, india.
General information crown flower is a fastgrowing, attractive, evergreen flowering shrub or small tree that grows about 5 metres tall, occasionally to 10 metres. As an important medicinal shrub and a fiber resource plant, there is an urgent need for developing molecular markers to facilitate breeding and genetic improvement of varieties. Table 1 showed preliminary phytochemical screening of plant parts of calotropis gigantea. Three hundred grams of powdered calotropis was separately macerated with 100% ethanol.
The antimicrobial effect of ethanol, aqueous and chloroform extracts of leaf and latex of calotropis procera on six bacteria namely, escherichia coli. Previous studies on the antimicrobial activity of c. Extracts on growth and survival dynamics of selected pathogenic microorganisms the growth profiles of c. The aim of the present study was to screen leaves of calotropis gigantea for the antimicrobial activity against clinical isolates of bacteria. Studies on endophytic fungi of calotropis procera l.
The antibacterial activity of methanol extract from the root bark of akanda calotropis gigantea l. The extractions from latex are quit tricky in context with preparation of latex for the extraction purpose. An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region in nepal, the latex is applied to sprains, body pains, boils and pimples. Chemical characterization and insecticidal activity of. Evaluation of antibacterial activity of calotropis.
Antioxidant, antimicrobial activities and gcms analysis of. Experimental and modeling studies on extraction of amyrins. An recent approach on calotropis gigantea and calotropis procera. Prominent analgesic activity was observed in eddys hot plate method and acetic acid induced writhings. Sep 22, 2015 the sodom apple calotropis gigantea, a member of the asclepiadaceae family, is a large evergreen shrub native to continental asia and northern africa. Pdf antidiabetic activity of calotropis gigantea in human. Each flower consists of five pointed petals and a small, elegant crown rising from the centre, which holds the stamens. The results of anti inflammatory effect of calotropis gigantea are showed in table 2. Calotropis gigantea is a well known medicinal herb commonly known as madar has been used in unani, ayurveda, and siddha system of medicine for years. Transcriptomic and metabolic responses of calotropis. Ocimum sanctum and calotropis gigantea leaves on clinical pathogens. Ramesh chandra bundelkhand university, jhansi, uttar pradesh, india. Phytochemical investigation of different plant parts of.
Other articles where calotropis gigantea is discussed. A downloadable pdf document of a book in prepublication awaiting illustration. Calotropis procera is a species of flowering plant in the family apocynaceae that is native to north africa, tropical africa, western asia, south asia, and indochina. The nematodes meloidogyne incognita and meloidogyne javanica are found on the roots of calotropis gigantea in india, although the leaf extract kills them. Calotropis gigantea is a common wasteland weed and known for various medicinal properties.
The first species being abundant while the second being restricted to forest areas. Asclepiadaceae a wildly growing plant has been reported to possess number of medicinal properties and other purposes. Antimicrobial activity of latex silver nanoparticles. Pdf antimicrobial activity of latex of calotropis gigantea against. Calotropis gigantea and calotropis procera are to a great extent having a very similar chemical properties, but the colours of their flowers are different. Calotropis procera is a well known plant and has been traditionally used for diarrhea, stomacic, sinus, fistula, and skin disease, alikhan and khanum 2005, raghubir et al. It has a deep taproot, 34 m deep, and a secondary root system with woody lateral roots that may rapidly regenerate adventitious shoots when the plant is injured. Pharmpcology, nri institute of pharmaceutical sciencesnips, bhopal 2asst professor, nips, bhopalmp krishna. The ayurveda medicine system and medicinal plants help to meet their primary health care needs farnsworth et al. Jun 15, 2006 alcoholic extract of peeled roots of calotropis gigantea r.
The ph of latex of these two species has been found different in the present study. The extracts were filtered with whatman filter paper to obtain a clear. The search for novel antibiotics like compounds from medicinal plants. The leaves are broadly elliptical to oblongobovate in shape, with the size of 9. Preliminary phytochemical screening of calotropis gigantea leaf suchita singh, sanchita singh, r. Calotropis procera, latex, antimicrobial, antioxidant, antifungal. Studies on antidiarrhoeal activity of calotropis gigantea r. Inhibitory effect of calotropis gigantea extract on. The antiulcer activity of ethanolic extract of calotropis gigantea r. International research journal of pharmaceutical and. But the 200 mg kg dose of ethanolic extract calotropis gigantea showed maximum anti inflammatory effect and was comparable to that produced by 100mg kg of. Efficacy of antibacterial activity of calotropis gigantea. Sadhna kaushik department of pharmacology, maharani laxmi bai medical college, jhansi, uttar pradesh, india. Calotropis belongs to asclepiadaceae or milkweed or ak family which includes 280 genera and 2,000 species of worldwide distribution but most abundant in the subtropics and tropics, and rare in cold countries.
Antibacterial activity of aqueous extract of calotropis. Asclepiadaceae, commonly known as milkweed or swallowwort, is a common wasteland weed singh et al. Calotropis gigantea linn apocynaceae is a glabrous or hoary, laticiferous shrubs or small trees, about 34 m tall commonly known as the swallowwort or milkweed. The latex of the plant is also reported to possess analgesic and wound healing activity 19, 20, as well as antiinflammatory 21 and antimicrobial activities 22. Antimicrobial activities of calotropis procera on selected. Cg on ovalbumin induced asthma and arachidonic acid induced paw edema in rats. Calotropis procera is a wild plant species in the family apocynaceae that is able to grow in harsh, arid and heat stressed conditions. Files are available under licenses specified on their description page. Extracts on growthand survival dynamics of selected pathogenic microorganisms david m1, bharath k r2, bhavani m3 1,3department of biotechnology, sir padampat singhania university, udaipur, 3601, india. I am a research scholar and want to collect flowers of calotropis gigantea flowers for my study. Chitme 1 institute of pharmacy, bundelkhand university, jhansi, uttar pradesh, india. Present study was undertaken to investigate the effect of methanolic extract of root of calotropis gigantea linn. The sodom apple calotropis gigantea, a member of the asclepiadaceae family, is a large evergreen shrub native to continental asia and northern africa. To evaluate antimicrobial and phytochemical activity of hexane and ethanolic extract of.
Antimicrobial activity and phytochemical analysis of. Aiton is a spreading shrub or mediumsized tree reaching 2. Pdf wound healing activity of latex of calotropis gigantea. Plants profile for calotropis gigantea giant milkweed. The root and latex of calotropis gigantea were screened for its antimicrobial and phytochemical activities. Antifungal, antioxidant and antibacterial activities of. Different biochemical screening have been carried out to identify the important phyto. Study on antibacterial activity of calotropis procera.
The chloroform extracted fraction of latex showed inhibitory effect against s. As a continuation, the chemical constituents present in ethyl acetate extract of calotropis gigantea l. Preliminary phytochemical screening of calotropis gigantea. It is a body reaction in order to eliminate or limit the spread of injurious agent as.
Antimicrobial activity and phytochemical analysis of calotropis gigantea root, latex extracts. Giganteol which was first obtained from the stem bark is one of them and a new triterpene alcohol, isogiganteol is the other. This page was last edited on 15 december 2019, at 08. Calotropis species recorded for a number of activities like. The hypoglycemic activity in normal rats was carried out by treatment using chloroform.
The extraction was performed for 24 h with methanol. Antidiabetic activity of ethanol extract of cassia klenii leaf in streptozotocininduced diabetic rats and isolation of an active fraction and toxicity evaluation of the extract. Invitro studies on calotropis procera leaf extracts as inhibitors of. Both of methanol extract and its chloroform fraction showed activity against sarcina lutea, bacillus megaterium and pseudomonas aeruginosa.
Chitme institute of pharmacy, bundelkhand university, jhansi, uttar pradesh, india ramesh chandra bundelkhand university, jhansi, uttar pradesh, india sadhna kaushik department of pharmacology, m. An in vitro study venkatesan saratha and sorimuthu pillai subramanian department of biochemistry, university of madras guindy campus, chennai, tamil nadu, india abstract medicinal plants are important source of potentially useful. Singh n, jain nk, kannojia p, garud n, pathak ak, mehta sc, in vitro antioxidant activity of calotropis gigantea hydroalcohlic leaves extract. It is widely used in many ayurvedic treatments, both externally ksharasutra and internally. The 11 analysis of antimicrobial activity of aqueous, methanolic and ethanolic extract of leaves and 12 flower of calotropis procera was carried out in disc method and also determined mic value at 600nm through optical density using spectrophotometer. Pdf antimicrobial activity of akanda calotropis gigantea l. Small trees or shrubs, these two species are native to southern asia and africa and were introduced to south america and the islands of the caribbean, where they have naturalized. Studies on antidiarrhoeal activity of calotropis gigantea. Alcoholic extract of peeled roots of calotropis gigantea r. Inhibitory effect of calotropis gigantea extract on ovalbumin.
Evaluation of antibacterial activity of calotropis gigentica against streptococcus mutans and lactobacillus acidophilus. Pdf antimicrobial properties of ocimum sanctum and. Antimicrobial activity of latex of calotropis gigantea against pathogenic. Calotropis gigantea is an important indian medicinal plant and widely used in ayurveda for management of various diseases. Phytochemical analysis, antibacterial and antioxidant activity of. In both models the common parameter determined was ulcer index. The purpose of the present study was to evaluate scientifically the antidiarrhoeal effects of c. Preliminary phytochemical screening and gc ms issn profiling. University rewa india nbri lucknow india abstract herbals plants are effective source of traditional and modern medicines, useful for primary health care. The paw licking time was delayed and the numbers of writhings were greatly reduced. Provided by smithsonian institution, department of botany. Antifungal, antioxidant and antibacterial activities of calotropis procera mushtaq ahmed, rehmat ali khan, s.
Studies on antidiarrheal activity of calotropis gigantea. The latex of calotropis gigantea contains cardio glycosides, volatile fatty acids and calcium oxalate. Calotropis gigantea white asclepiadaceae, is a weed plant commonly known as giant milkweed. Calotropis gigantea grows to a height of 8 to 10 ft 2. The leaves are sessile and subsessile, opposite, ovate, cordate at the base. Cns activity of calotropis gigantea roots sciencedirect. The aim of our present study is to evaluate the antidiabetic activity of proteases extracted from specific protein antigen, bovine serum albumin bsa using calotropis gigantea, flowers dissolved.
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